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Omesoft 1gm Soft Gelatin Capsule 5pcs
Omega-3-acid ethyl esters lower triglyceride levels by reducing production in the liver, though the exact mechanism is not fully understood. This medication:
- Inhibits acyl-CoA: 1,2-diacylglycerol acyltransferase, decreasing triglyceride synthesis.
- Increases paroxysmal beta-oxidation, enhancing fatty acid metabolism.
- Competes with enzymes involved in triglyceride synthesis, thereby reducing fatty acid release.
- Boosts triglyceride clearance by increasing lipoprotein lipase activity.
- Decreases production of very-low-density lipoprotein cholesterol (VLDL-C).
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✅ Description:
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✔️
Omesoft is prescribed as a supplementary treatment alongside a proper diet to:
- In adult patients, reduce extremely high triglyceride (TG) levels (above 500 mg/dl).
- Aid in secondary prevention for patients who have experienced a myocardial infarction (heart attack) within the past three months.
- Alleviate joint inflammation associated with mild arthritis.
- Support the management of mood disorders and impulse control issues.
- Slow the progression of age-related macular degeneration.
Always take this medication as directed by a licensed physician.
✔️ Side Effects of Omesoft 1gm Soft Gelatin Capsule
Immune System Disorders:
- Rare: Hypersensitivity reactions
Metabolism and Nutrition Disorders:
- Uncommon: Hyperglycemia, gout
Nervous System Disorders:
- Uncommon: Dizziness, altered taste, headache
Vascular Disorders:
- Uncommon: Hypotension
Respiratory Disorders:
- Uncommon: Nosebleeds
Gastrointestinal Disorders:
- Common: Abdominal pain, distension, constipation, diarrhea, flatulence, belching, nausea, vomiting, acid reflux
- Uncommon: Gastrointestinal bleeding
Hepatobiliary Disorders:
- Rare: Elevated liver enzymes (e.g., ALT, AST), liver abnormalities
Skin Disorders:
- Uncommon: Rash
- Rare: Hives
✔️ Dosage and Administration of Omega-3 Acid Ethyl Esters
- For hypertriglyceridemia: 4 capsules (4 g) as a single dose, or 2 capsules (2 g) twice daily.
- Post-myocardial infarction: 1 capsule (1 g) daily with food. Patients should adhere to a lipid-lowering diet before and during treatment.
- For joint inflammation (mild arthritis): 2.7 g daily.
- For mood disorders, impulse control, or macular degeneration: 1 capsule (1 g) per day.
Always follow the dosage instructions provided by your doctor.
✔️ Drug Interactions
- Omesoft can be safely used with warfarin without causing hemorrhagic complications. However, the prothrombin time should be monitored when starting or discontinuing Omesoft alongside warfarin.
✔️ Contraindications
Individuals with hypersensitivity should not use Omesoft or any of its components.
✔️ Pregnancy and Lactation
- Omega-3-acid ethyl esters should only be used during pregnancy if the potential benefits outweigh the risks to the fetus.
- It is unknown if the medication passes into breast milk; therefore, caution is advised for breastfeeding mothers.
✔️ Precautions and Warnings
- High doses (e.g., 4 capsules daily) can moderately increase bleeding time, so patients on anticoagulant therapy require close monitoring. Adjust anticoagulant dosage if needed.
- Take extra care in patients at a high risk of bleeding (e.g., severe trauma, surgery).
- In some studies, Omega-3 acids were associated with prolonged bleeding time, but these increases remained within normal limits and did not cause significant bleeding episodes.
- Patients with signs of liver damage should have their ALT and AST levels monitored, particularly when taking high doses.
- This medication is not recommended for use in children due to a lack of safety data.
- Omesoft is not indicated for type 1 hyperchylomicronemia (exogenous hypertriglyceridemia) and has limited experience in secondary endogenous hypertriglyceridemia, such as that caused by uncontrolled diabetes.
✔️ Storage Conditions
Store below 25°C in a cool, dry place. Keep away from moisture and direct sunlight.
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